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Antibiotic Resistance: The Need For a Global Strategy
The development of antibiotic resistance is a major problem for mankind and results in fatal consequences on a daily basis across the globe. There are a no. of reasons for this situation including increasing globalization ...
Methodology of oral formulation selection in the pharmaceutical industry
Pharmaceutical formulations have to fulfil various requirements with respect to their intended use, either in the development phase or as a commercial product. New drug candidates with their specific properties confront ...
Application of the solubility parameter concept to assist with oral delivery of poorly water‐soluble drugs – a PEARRL review
Objectives: Solubility parameters have been used for decades in various scientific fields includ-ing pharmaceutics. It is, however, still a field of active research both on a conceptual and experi-mental level. This work ...
Approaches to increase mechanistic understanding and aid in the selection of precipitation inhibitors for supersaturating formulations – a PEARRL review
Objectives Supersaturating formulations hold great promise for delivery of poorly soluble active pharmaceutical ingredients (APIs). To profit from supersaturating formulations, precipitation is hindered with precipitation ...
Lipophilicity and hydrophobicity considerations in bio‐enabling oral formulations approaches – a PEARRL review
Objectives This review highlights aspects of drug hydrophobicity and lipophilicity as determinants of different oral formulation approaches with specific focus on enabling formulation technologies. An overview is provided ...
Application of the solubility parameter concept to assist with oral delivery of poorly water-soluble drugs - a PEARRL review.
Objectives Solubility parameters have been used for decades in various scientific fields including pharmaceutics. It is, however, still a field of active research both on a conceptual and experimental level. This work ...