Auflistung Institut für Pharma Technology nach Titel
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3D manufacturing of metallic implants
(2016-05)The design, manufacturing and testing of load-bearing implants made of titanium, titanium alloy and magnesium produced by selective laser melting (SLM) will be presented. Analytical, structural, mechanical, in-silico, ... -
A diffusing wave spectroscopy study of pharmaceutical emulsions for physical stability assessment
(2017)Emulsions are broadly used in pharmaceutics either as intermediate products or as final dosage forms. Such disperse systems are only kinetically stabilized and therefore early detection of physical instability is highly ... -
A microstructural study of water effects in lipid-based pharmaceutical formulations for liquid filling of capsules
(2016-07-30)Water is known to exhibit pronounced effects on lipid-based formulations (LBFs) and much research has focused on aqueous dispersion and dilution behavior regarding biopharmaceutical performance. From a product quality ... -
A Systematic Study of Molecular Interactions of Anionic Drugs with a Dimethylaminoethyl Methacrylate Copolymer Regarding Solubility Enhancement
(2017)The methacrylate-copolymer Eudragit EPO (EPO) has raised interest in solubility enhancement of anionic drugs. Effects on aqueous drug solubility at rather low polymer concentrations are barely known despite their importance ... -
A Systematic Study on Manufacturing of Prilled Microgels into Lipids for Oral Protein Delivery.
(Wiley, 2015-10)The development of novel systems with oral protein delivery as ultimate goal represents an important field of pharmaceutics. Prilling of protein-loaded polymeric solutions into lipid-based hardening baths could provide ... -
Antibiotic Resistance: The Need For a Global Strategy
(2016)The development of antibiotic resistance is a major problem for mankind and results in fatal consequences on a daily basis across the globe. There are a no. of reasons for this situation including increasing globalization ... -
Application of natural and semi-synthetic polymers for the delivery of sensitive drugs
(Taylor & Francis, 2015-02)Abstract This review summarises recent developments in the application of natural and semi-synthetic polymers for the delivery of sensitive drugs. Peptides, proteins and nucleic acids are drugs of increasing relevance ... -
Application of the solubility parameter concept to assist with oral delivery of poorly water-soluble drugs - a PEARRL review.
(2018-07)Objectives Solubility parameters have been used for decades in various scientific fields including pharmaceutics. It is, however, still a field of active research both on a conceptual and experimental level. This work ... -
Application of the solubility parameter concept to assist with oral delivery of poorly water‐soluble drugs – a PEARRL review
(2018-07-05)Objectives: Solubility parameters have been used for decades in various scientific fields includ-ing pharmaceutics. It is, however, still a field of active research both on a conceptual and experi-mental level. This work ... -
Application of the solubility parameter concept to assistwith oral delivery of poorly water-soluble drugs–a PEARRLreview
(2018-02-28)ObjectivesSolubility parameters have been used for decades in various scientificfields including pharmaceutics. It is, however, still a field of active research bothon a conceptual and experimental level. This work addresses ... -
Approaches to increase mechanistic understanding and aid in the selection of precipitation inhibitors for supersaturating formulations – a PEARRL review
(2018-05)Objectives Supersaturating formulations hold great promise for delivery of poorly soluble active pharmaceutical ingredients (APIs). To profit from supersaturating formulations, precipitation is hindered with precipitation ... -
Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review
(American Chemical Society, 2015) -
Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review
(American Chemical Society, 2015-01-08)This multiauthor review article aims to bring readers up to date with some of the current trends in the field of process analytical technology (PAT) by summarizing each aspect of the subject (sensor development, PAT based ... -
Benefits of Fractal Approaches in Solid Dosage Form Development.
(2019-09-06)Pharmaceutical formulations are complex systems consisting of active pharmaceutical ingredient(s) and a number of excipients selected to provide the intended performance of the product. The understanding of materials' ... -
Biorelevant drug solubility enhancement modeled by a linear solvation energy relationship
(2017)It is for the pharmaceutical sciences of vital importance to understand how drugs are solubilized in biorelevant media. However, the complexity of fasted state simulated intestinal fluid (FaSSIF) has so far hampered adequate ... -
Calculation of drug-polymer mixing enthalpy as a new screening method of precipitation inhibitors for supersaturating pharmaceutical formulations.
(2019-03-12)Supersaturating formulations are widely used to improve the oral bioavailability of poorly soluble drugs. However, supersaturated solutions are thermodynamically unstable and such formulations often must include a precipitation ...