Auflistung Institut für Pharma Technology nach Erscheinungsdatum
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Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review
(American Chemical Society, 2015) -
Influence of salt type and ionic strength on self-assembly of dextran sulfate-ciprofloxacin nanoplexes
(Elsevier, 2015)We evaluated an analytical setup to identify optimal preparation conditions for nanoplex formation of small molecule drugs and polyelectrolytes using ciprofloxacin (CIP) and dextran sulfate (DS) as model compounds. The ... -
The effect of silk gland sericin protein incorporation into electrospun polycaprolactone nanofibers on in vitro and in vivo characteristics
(Royal Society of Chemistry, 2015) -
Predictive Toxicology: From Vision to Reality
(John Wiley & Sons, 2015) -
Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review
(American Chemical Society, 2015-01-08)This multiauthor review article aims to bring readers up to date with some of the current trends in the field of process analytical technology (PAT) by summarizing each aspect of the subject (sensor development, PAT based ... -
Application of natural and semi-synthetic polymers for the delivery of sensitive drugs
(Taylor & Francis, 2015-02)Abstract This review summarises recent developments in the application of natural and semi-synthetic polymers for the delivery of sensitive drugs. Peptides, proteins and nucleic acids are drugs of increasing relevance ... -
Simple and rapid high performance liquid chromatography method for the determination of polidocanol as bulk product and in pharmaceutical polymer matrices using charged aerosol detection
(Elsevier, 2015-02)Currently, neither the European nor the United States Pharmacopoeia provide a method for the determination of polidocanol (PD) content despite the fact that PD, besides being an excipient, is also used as an active ... -
Permeation Characteristics of Hypericin across Caco-2 Monolayers in the Absence or Presence of Quercitrin - A Mass Balance Study
(Georg Thieme Verlag KG, 2015-08) -
A Systematic Study on Manufacturing of Prilled Microgels into Lipids for Oral Protein Delivery.
(Wiley, 2015-10)The development of novel systems with oral protein delivery as ultimate goal represents an important field of pharmaceutics. Prilling of protein-loaded polymeric solutions into lipid-based hardening baths could provide ... -
Flow-through cross-polarized imaging as a new tool to overcome the analytical sensitivity challenges of a low-dose crystalline compound in a lipid matrix
(Elsevier, 2015-11-10)Assessing the physical state of a low-dose active compound in a solid lipid or polymer matrix is analytically challenging, especially if the matrix exhibits some crystallinity. The aim of this study was first to compare ... -
Development and full validation of an UPLC-MS/MS method for the quantification of the plant-derived alkaloid indirubin in rat plasma
(2016)An UPLC-MS/MS method for the quantification of indirubin in lithium heparinized rat plasma was developed and validated according to current international guidelines. Indirubin was extracted from rat plasma by using Waters ... -
Pharmacokinetics and in vitro blood-brain barrier screening of the plant-derived alkaloid tryptanthrin
(2016)The indolo[2,1-b]quinazoline alkaloid tryptanthrin was previously identified as a potent anti-inflammatory compound with a unique pharmacological profile. It is a potent inhibitor of cyclooxygenase-2, 5-lipooxygenase-catalyzed ...