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A Biocatalytic Nanomaterial for the Label-Free Detection of Virus-Like Particles
The design of nanomaterials that are capable of specific and sensitive biomolecular recognition is an on-going challenge in the chemical and biochemical sciences. A number of sophisticated artificial systems have been ...
Enzyme Shielding in an Enzyme-thin and Soft Organosilica Layer
The fragile nature of most enzymes is a major hindrance to their use in industrial processes. Herein, we describe a synthetic chem. strategy to produce hybrid org./inorg. nanobiocatalysts; it exploits the self-assembly ...
Virus-like particles as virus substitutes to design artificial virus-recognition nanomaterials
(Royal Society of Chemistry, 2015-01-05)
Functional recognition imprints of virus-like particles, at the surface of silica particles, were generated following a strategy based on protein-templated polycondensation of organosilanes.
Surface Immobilization and Shielding of a Transaminase Enzyme for the Stereoselective Synthesis of Pharmaceutically Relevant Building Blocks
Transaminases are enzymes capable of stereoselective reductive amination; they are of great interest in the production of chiral building blocks. However, the use of this class of enzymes in industrial processes is often ...