Auflistung Hochschule für Life Sciences nach Titel
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Ultra-sub-stoichiometric “Dynamic” Bioconjugation Reduces Viscosity by Disrupting Immunoglobulin Oligomerization.
(2019-09-09)Monoclonal antibodies (mAb) are a major focus of the pharmaceutical industry, and polyclonal immunoglobulin G (IgG) therapy is used to treat a wide variety of health conditions. As some individuals require mAb/IgG therapy ... -
Ultrasound melted polymer sleeve for improved screw anchorage in trabecular bone-A novel screw augmentation technique
(2016-02-23)BACKGROUND: Screw anchorage in osteoporotic bone is still limited and makes treatment of osteoporotic fractures challenging for surgeons. Conventional screws fail in poor bone quality due to loosening at the screw-bone ... -
Understanding selenium biogeochemistry in engineered ecosystems: Transformation and analytical methods
(2017)Selenium is used extensively in many industries, and it is necessary for human nutrition. On the other hand, it is also toxic at slightly elevated concentrations. With the advent of industrialisation, selenium concentrations ... -
Unexpected solubility enhancement of drug bases in presence of a dimethylaminoethyl methacrylate copolymer
(2017)The methacrylate copolymer Eudragit EPO (EPO) has previously shown to greatly enhance solubilization of acidic drugs via ionic interactions and by multiple hydrophobic contacts with polymeric side chains. The latter type ... -
Using Physiologically Based Pharmacokinetic (PBPK) Modelling to Gain Insights into the Effect of Physiological Factors on Oral Absorption in Paediatric Populations
(2016-07-08)Paediatric pharmaceutics has become an important topic, but currently, there is an incomplete knowledge of paediatric gastrointestinal physiology and adequate biopharmaceutical tools still have to be developed. The present ...