Auflistung nach Autor/in "Suter-Dick, Laura"
Anzeige der Eintraege 1-20 von 20
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3D human liver microtissues vs. 2D monolayer culture as an in vitro tool for compound testing
Messner, Catherine; Prestigiacomo, Vincenzo; Mannino, Salvatore; Mauch, Linda; Suter-Dick, Laura (2018-10) -
A three-dimensional, human co-culture model for the study of mechanisms in Alzheimer's disease
Suter-Dick, Laura; Gaiser, Carine (2018-07) -
AhR-Mediated Effects of Dioxins on liver in zebrafish embryos
Yan, Lu; Zenker, Armin; Suter-Dick, Laura (2018-11) -
Assessment of human relevant effects of PTS using relevant in vitro systms
Suter-Dick, Laura (2018-11) -
Combining Extracellular miRNA Determination with Microfluidic 3D Cell Cultures for the Assessment of Nephrotoxicity: a Proof of Concept Study
Suter-Dick, Laura; Mauch, Linda; Ramp, D; Caj, Michaela; Vormann, Marianne K.; Hutter, Simon; Lanz, H.L.; Vried, J.; Masereeuw, R.; Wilmer, Martijn J. (2018-07)Drug-induced kidney injury is often observed in the clinics and can lead to long-term organ failure. In this work, we evaluated a novel in vitro system that aims at detecting whether compounds can cause renal proximal ... -
Design of kidney structures to be cultured under flow conditions in a microfluid-ic device.
Suter-Dick, Laura; Chavanne, Philippe; Hugot Beaufils, Marina; Hradetzky, David (2016) -
Design of kidney structures to be cultured under flow conditions in a microfluidic device.
Suter-Dick, Laura; Hugot Beaufils, Marina; Chavanne, Philippe; Hradetzky, David (2016) -
High-Throughput Screening of Drug-Transporter Interactions in a 3D Microfluidic Renal Proximal Tubule on a Chip
Vriend, Jelle; Nieskens, Tom T.G.; Vormann, Marianne K.; van den Berge, Batholomeus T.; van den Heuvel, Angelique; Russel, Frans G.M.; Suter-Dick, Laura; Lanz, Henriette; Vulto, Paul; Masereeuw, Rosalinde; Wilmer, Martijn J. (2018-07)Drug-transporter interactions could impact renal drug clearance and should ideally be detected in early stages of drug development to avoid toxicity-related withdrawals in later stages. This requires reliable and robust ... -
Human 3D-cocultures for the study of liver fibrosis
Suter-Dick, Laura; Human, L. (2016) -
Human 3D-cocultures for the study of toxicant induced liver fibrosis
Suter-Dick, Laura; Prestigiacomo, Vincenzo; Lampart, F. (2016) -
Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans
Suter-Dick, Laura; Atienzar, Franck A; Blomme, Eric A. (2016-09) -
Microfluidic systems and novel biomarkers for the assessment of proximal tubular toxicity
Suter-Dick, Laura (2018-11) -
Microphysiological system based on human liver microtissues for intrinsic clearance prediction
Hürlimann, Fabrizio; Mannino, Salvatore; Lohasz, Christian; Renggli, Kasper; Hierlemann, Andreas; Suter-Dick, Laura; Frey, Olivier (2018-06) -
Modelling Alzheimer’s disease in three-dimensional human neural progenitor cultures
Gaiser, Carine; Weston, Anna; Suter-Dick, Laura (2018-09) -
Nephrotoxicity and Kidney Transport Assessment on 3D Perfused Proximal Tubules
Vormann, Marianne K.; Gijzen, Linda; Hutter, Simon; Boot, Lisette; Nicolas, Arnaud; van den Heuvel, Angelique; Vriend, Jelle; Ng, Chee Ping; Nieskens, Tom T.G.; van Duinen, Vincent; de Wagenaar, Bjorn; Masereeuw, Rosalinde; Suter-Dick, Laura; Trietsch, Sebastian J.; Wilmer, Martijn; Joore, Jos; Vulto, Paul; Lanz, Henriette (2018-08)Proximal tubules in the kidney play a crucial role in reabsorbing and eliminating substrates from the body into the urine, leading to high local concentrations of xenobiotics. This makes the proximal tubule a major target ... -
Nrf2 protects stellate cells from Smad-dependent cell activation.
Prestigiacomo, Vincenzo; Suter-Dick, Laura (2018-07)Hepatic stellate cells (HSC) orchestrate the deposition of extracellular matrix (ECM) and are the primary effector of liver fibrosis. Several factors, including TGF-β1, PDGF and oxidative stress, have been shown to trigger ... -
Predicting hepatic compound clearance using a microphysiological system based on human liver microtissues
Hürlimann, Fabrizio; Mannino, Salvatore; Suter-Dick, Laura; Frey, Olivier (2018) -
Standardized 3D-cell culture systems for the evaluation of cytostatica
Suter-Dick, Laura; Vazzana, R. (2016) -
Test de toxicidad empleando modelos 3D hechos a medida: Hígado y Riñón
Suter-Dick, Laura (2018-10) -
The role of bile salts in cholestatic injury and fibrosis using a human 3D in vitro model
Messner, Catherine; Mauch, Linda; Mannino, Salvatore; Prestigiacomo, Vincenzo; Suter-Dick, Laura (2018-11)