Auflistung nach Autor/in "Hamburger, M"

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Pharmacokinetics and in vitro blood-brain barrier screening of the plant-derived alkaloid tryptanthrin

Jähne, E; Eigenmann, D; Sampath, C; Butterweck, Veronika; Culot, M; Cecchelli, R; Gosselet, F; Walter, F. R.; Deli, MA; Smiesko, M; Hamburger, M; Oufir, M (2016)

The indolo[2,1-b]quinazoline alkaloid tryptanthrin was previously identified as a potent anti-inflammatory compound with a unique pharmacological profile. It is a potent inhibitor of cyclooxygenase-2, 5-lipooxygenase-catalyzed ...
Validation of UHPLC-MS/MS methods for the determination of kaempferol and its metabolite 4-hydroxyphenyl acetic acid, and application to in vitro blood-brain barrier and intestinal drug permeability studies

Moradi-Afrapoli, Fahimeh; Oufir, M; Walter, F.R.; Deli, MA; Smiesko, M; Zabela, V; Butterweck, Veronika; Hamburger, M (2016)

Sedative and anxiolytic-like properties of flavonoids such as kaempferol and quercetin, and of some of their intestinal metabolites, have been demonstrated in pharmacological studies. However, routes of administration were ...